UKC2014 San Francisco - Forward Together

Basic research in biological sciences has greatly enhanced our understanding of molecular, cellular, and genetic mechanisms underpinning various aspects of living organisms in health and disease. Many of the outstanding questions in biomedical research call for collaboration between scientists in different fields of basic science as well as clinical and pharmaceutical disciplines. The goal of BMP symposium is to introduce the latest advances in biological, medical, and pharmaceutical sciences, which will facilitate future collaborative discoveries across the disciplines. As a part of the Emerging Technology Program, we will focus on the use of the latest techniques and approaches to enhance our understanding of the fundamental biological principles as well as translational advances to improve human health. The symposium will provide an overview of broad ranges of topics including cancer, immunology, neuroscience, stem cell research, drug discovery, and translational medicine. In addition, how such advances may be utilized for designing effective therapeutic strategies will be discussed.

Chair
	Sohyun Ahn National Institutes of Health USA
Co-Chair
	Hey-Kyoung Lee The Johns Hopkins University USA

Keynote Speakers
Name	Affiliation	Title
Sohyun Ahn	NIH/NICHD	Setting up the Neurogenic Niche
Hey-Kyoung Lee	Johns Hopkins Univ	Cross-Modal Cortical Adaptation to Sensory Loss

Session Chairs
Name	Affiliation	Session
Jung Hyun Park	NIH/NCI	Immune system: Development and homeostasis
Seung-Hoi Koo	Korea University	Molecular Basis of Metabolic Disease
Sohyun Ahn	NIH/NICHD	Stem Cells and Development
Hey-Kyoung Lee	Johns Hopkins Univ	Advances in Neuroscience
Kyung S. Lee	NIH/NCI	Cell cycle and Cancer
Sihoun Hahn		Advances in Translational Research
Soo-Kyung Lee	OHSU	Epigenetic regulation in development, disease and more
Yun H. Choe	Lucas & Mercanti, LLP	Drug Discovery and Development

Invited Speakers
Name	Affiliation	Title
Immune system: Development and homeostasis
Jung Hyun Park	NIH/NCI	Cytokine signaling in CD4/CD8 lineage decision in the thymus
Chang H. Kim	Purdue University	Bidirectional regulation of immunity by the gut bacterial metabolites short chain fatty acids
Jeong-Sook Shin	UCSF	Homeostasis and function of immunoglubulin E
Cheong Hee Chang	Univ Michigan	Interplay of signlaing and cell metabolism for the development and function of innate T cells
Charles C. Kim	UCSF	Immunological tolerance of malaria infection
Name	Affiliation	Title
Molecular Basis of Metabolic Disease
Kee Hong Kim	Purdue Univ	Leaving Resveratrols Shadow: Role of Piceatannol, a Resveratrol Analogue, in Adipogenesis and Lipid Metabolism in Adipocytes
Jun Hee Lee	Univ Michigan	Orchestration of cellular metabolism by Sestrin-family proteins
Seung-Hoi Koo	Korean Univ	Regulation of Hepatic Gluconeogenesis by Protein Argnine Methyltransferase 6
Jae Myoung Suh	Salk Institute	Endocrinization of FGF1 produces a neomorphic insulin sensitizing activity
Name	Affiliation	Title
Stem Cells and Development
Mi-Ryoung Song	GIST	STAT3 maintains the stemness of radial glia at mid-neurogenesis
Mi Hyeon Jang	Mayo Clinic College of Medicine	Molecular mechanism governing new neuron development in adult brain
Gabsang Lee	Johns Hopkins Univ School of Medicine	Derivation of induced neural crest from human postnatal fibroblasts
Deok-Ho Kim	Univ Washington	Microenvironmental regulation of stem cell function and tissue regeneration
Senyon Choe	Salk Institute & UCSD	Engineering Body Morphogenetic Proteins (BMPs) and their clinical potentials
Name	Affiliation	Title
Advances in Neuroscience
Eunjoon Kim	KAIST	Synaptic scaffoding protein, NMDA receptor function, and autism spectrum disorders
Se-Young Choi	Seoul National Univ	Synaptic role of mild mental retardation related factor, Cereblon
Alfredo Kirkwood	Johns Hopkins Univ	Neuromodulation of cortical plasticity
Hee Jung Chung	Univ Illinois-Urbana-Champaign	The role of KCNQ channels in epilepsy and homeostatic plasticity
Hey-Kyoung Lee	Johns Hopkins Univ	Experience-dependent homeostatic plasticity of inhibitory synapses
Cell cycle and Cancer
Wallace Marshall	UCSF	Patterning centriole assembly in Stentor
Kunsoo Rhee	Seoul National Univ	Spindle Pole Formation and Disintegration during Mitosis
Kyung S. Lee	NIH/NCI	Polo-like kinase 4 and 1: From centrosome duplication to mitotic control
Dongmin Kang	Ewah Womans University	Control of the pericentrosomal H2O2 level by peroxiredoxin I Is critical for mitotic progression
Kyungjae Myung	NIH/NHGRI	Identification of a potential chemotherapeutic agent to treat lynch syndrome tumors
Advances in Translational Research
Sihoun Hahn	Seattle Children's Hospital, University of Washington	Precision Medicine through Next-Generation Sequencing Raising the bar for education, training and practice
Jung-Min Lee	NIH/NCI	Targeting DNA damage repair and cell cycle pathways in womens cancers
Joo Ha Hwang	University of Washington Sch Med	Potential applications of high-intensity focused ultrasound (HIFU) in the treatment of pancreatic cancer
W. Ray Kim	Stanford University School of Medicine	Direct Acting Antivirals for HCV: A triumph in the making for translational research
Chang Ho Seo	University of Tokyo	Biofunctional Surfaces with Nano- and Micro-topographic Cues to Promote Osteogenic Differentiation and Focal Adhesion Maturation
Epigenetic regulation in development, disease and more
Seunghee Lee	Seoul National Univ	UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program
Jaehoon Kim	KAIST	How to write histone H3K4 methyl mark on chromatin
Soo-Kyung Lee	OHSU	Ezh2, a histone H3-lysine 27 methyltransferase, functions as an epigenetic timer to coordinate the timely differentiation of oligodendrocytes
Inhyun Park	Yale Univ	Dynamic change in X Chromosome Status in Reprogramming
Hee-Woong Lim	Univ Penn	Genome-wide analysis of enhancer-RNA transcription reveals regulatory mechanisms by an anti-diabetic drug in adipocyte
Drug Discovery and Development
Yun H. Choe	Lucas & Mercanti, LLP	Patent Talk, Patent and Drug Discovery and Development-after AIA
K. Stephen Suh	JT Cancer Center, HUMC	Circulating Tumor Cells in Hodgkin Lymphoma and Prognostic Biomarkers: New Windows for Precision Drugs
Yosup Rew	Amgen	Discovery of AMG 232, a small molecule MDM inhibitor for treating cancer
Danny Joh	BioMarin	A Case Study on Clinical Development of a Kinase Inhibitor: A Brief History of Iressa
Wooseok Han	Novartis	Structure Guided Optimization of Novel, Selective, and Orally Bioavailable Inhibitors of PIM Kinases
Heemin Rhee	Health Research International	Scientific Innovation, Regulatory Expeditious Review, and Cost Effectiveness for Drug Discovery and Development